Victoria L Bae-Jump Selected Research

ONC206

1/2022	ONC206 has anti-tumorigenic effects in human ovarian cancer cells and in a transgenic mouse model of high-grade serous ovarian cancer.
1/2021	Highly potent dopamine receptor D2 antagonist ONC206 demonstrates anti-tumorigenic activity in endometrial cancer.

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Victoria L Bae-Jump Research Topics

Disease

34	Neoplasms (Cancer) 01/2022 - 07/2004
28	Endometrial Neoplasms (Endometrial Cancer) 01/2022 - 07/2004
19	Ovarian Neoplasms (Ovarian Cancer) 01/2022 - 03/2006
7	Obesity 01/2021 - 04/2014
5	Carcinogenesis 12/2021 - 11/2006
3	Neoplasm Metastasis (Metastasis) 05/2021 - 01/2015
3	Ovarian Epithelial Carcinoma 10/2015 - 12/2013
2	Uterine Cervical Neoplasms (Cancer of the Cervix) 04/2017 - 03/2006
2	Breast Neoplasms (Breast Cancer) 01/2015 - 07/2004
1	Thrombosis (Thrombus) 02/2022
1	COVID-19 02/2022
1	Hematologic Neoplasms (Hematological Malignancy) 01/2021
1	Hypersensitivity (Allergy) 01/2020
1	Immediate Hypersensitivity 01/2020
1	Carcinosarcoma 12/2019
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2019
1	Type 2 Diabetes Mellitus (MODY) 11/2017
1	Lactic Acidosis 11/2017
1	Papillomavirus Infections 04/2017
1	Weight Loss (Weight Reduction) 12/2016
1	Uterine Neoplasms (Uterine Cancer) 01/2016
1	Thrombocytosis (Thrombocythemia) 12/2015

Drug/Important Bio-Agent (IBA)

9	Metformin (Glucophage)FDA LinkGeneric 01/2021 - 01/2010
8	Messenger RNA (mRNA)IBA 06/2016 - 03/2006
7	Proteins (Proteins, Gene)FDA Link 06/2016 - 12/2008
6	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2015 - 03/2006
5	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 01/2015
5	Estrogens (Estrogen)FDA Link 01/2018 - 07/2004
4	Paclitaxel (Taxol)FDA LinkGeneric 01/2020 - 03/2010
4	MTOR InhibitorsIBA 04/2016 - 09/2009
4	Sirolimus (Rapamycin)FDA Link 12/2010 - 03/2006
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 06/2016
3	TIC10 compoundIBA 01/2022 - 01/2021
3	BiguanidesIBA 01/2021 - 09/2016
3	Biological ProductsIBA 01/2021 - 04/2017
3	LipidsIBA 01/2019 - 05/2006
3	Fatty Acids (Saturated Fatty Acids)IBA 12/2017 - 02/2015
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2017 - 08/2014
2	LigandsIBA 01/2022 - 01/2021
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 01/2021
2	Peptide Hydrolases (Proteases)FDA Link 01/2022 - 01/2022
2	ONC206IBA 01/2022 - 01/2021
2	Estrogen Receptor alphaIBA 01/2018 - 12/2008
2	Atorvastatin (Lipitor)FDA Link 01/2018 - 01/2017
2	GenisteinIBA 01/2018 - 01/2016
2	Caspase 3 (Caspase-3)IBA 11/2017 - 08/2014
2	Glutamine (L-Glutamine)FDA Link 09/2017 - 08/2015
2	EnzymesIBA 12/2016 - 11/2006
2	Simvastatin (Zocor)FDA LinkGeneric 01/2016 - 08/2014
2	Biomarkers (Surrogate Marker)IBA 01/2016 - 12/2010
2	1-dodecylpyridoxal (PLD)IBA 10/2015 - 12/2013
2	Mitogen-Activated Protein KinasesIBA 01/2013 - 12/2008
2	Estrogen ReceptorsIBA 01/2013 - 11/2006
2	TOR Serine-Threonine KinasesIBA 03/2010 - 09/2009
1	Thromboplastin (Tissue Factor)IBA 02/2022
1	Small Cytoplasmic RNAIBA 12/2021
1	ChromatinIBA 12/2021
1	ethyl monochloroacetate (EMCA)IBA 05/2021
1	Dopamine Receptors (Dopamine Receptor)IBA 01/2021
1	ProdrugsIBA 01/2020
1	Pharmaceutical PreparationsIBA 01/2020
1	cremophor ELIBA 01/2020
1	Generic DrugsIBA 01/2019
1	Progesterone Receptors (Progesterone Receptor)IBA 01/2018
1	IsoenzymesIBA 01/2018
1	IsoflavonesIBA 01/2018
1	Carbonic Anhydrases (Carbonic Anhydrase)IBA 01/2018
1	Carbonic Anhydrase IXIBA 01/2018
1	Topiramate (Topamax)FDA LinkGeneric 01/2018
1	K-18 conjugate (K18)IBA 12/2017
1	Phenformin (Fenformin)IBA 11/2017
1	Adenosine Triphosphate (ATP)IBA 09/2017
1	Pyruvic Acid (Pyruvate)IBA 09/2017
1	Aminooxyacetic AcidIBA 09/2017
1	MicroRNAs (MicroRNA)IBA 04/2017
1	Fatty Acid Synthases (Fatty Acid Synthase)IBA 12/2016
1	Orlistat (Xenical)FDA Link 12/2016
1	Cyclin D1IBA 10/2016
1	Cyclin-Dependent Kinase 4IBA 10/2016
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 06/2016
1	Celecoxib (Celebrex)FDA Link 06/2016
1	Phosphotransferases (Kinase)IBA 04/2016
1	Mechanistic Target of Rapamycin Complex 1IBA 04/2016
1	Everolimus FDA Link 04/2016
1	Mevalonic Acid (Mevalonate)IBA 01/2016
1	BuforminIBA 01/2016
1	Transcription Factors (Transcription Factor)IBA 01/2016
1	Diethylstilbestrol (Stilbestrol)FDA Link 01/2016
1	compound 968IBA 01/2016
1	Phytoestrogens (Phytoestrogen)IBA 01/2016
1	GlutaminaseIBA 01/2016
1	Oncogene Proteins (Oncogene Protein)IBA 01/2016
1	Estradiol Congeners (Synthetic Estrogens)IBA 01/2016
1	P-30 composite resin (P 30)IBA 12/2015
1	ChemokinesIBA 10/2015
1	liposomal doxorubicin (Doxil)FDA Link 10/2015

Therapy/Procedure

10	Therapeutics 01/2020 - 09/2009
4	Fat-Restricted Diet (Diet, Fat Restricted) 01/2022 - 04/2014
3	Drug Therapy (Chemotherapy) 01/2022 - 02/2010
1	Aftercare (After-Treatment) 06/2016